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       IM Publications LLP :: Mass Spectrometry :: Mass Spectrometry: Principles and Applications, 3rd Edn

 

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Mass Spectrometry: Principles and Applications, 3rd Edn
Mass Spectrometry: Principles and Applications, 3rd Edn 
The lastest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications.

This book is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments
 
 
Contents

  • Preface
  • Introduction
  • Principles
  • Diagram of a Mass Spectrometer
  • History
  • Ion Free Path
  • Ion Sources
  • Electron Ionization
  • Chemical Ionization
  • Proton transfer
  • Adduct formation
  • Charge-transfer chemical ionization
  • Reagent gas
  • Negative ion formation
  • Desorption chemical ionization (DCI)
  • Field Ionization
  • Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry
  • Field Desorption
  • Plasma Desorption
  • Laser Desorption
  • Matrix-Assisted Laser Desorption Ionization
  • Principle of MALDI
  • Practical considerations
  • Fragmentations
  • Atmospheric pressure matrix-assisted laser desorption ionization
  • Thermospray
  • Atmospheric Pressure Ionization
    • Electrospray
  • Multiply charged ions
  • Electrochemistry and electric field as origins of multiply charged ions
  • Sensitivity to concentration
  • Limitation of ion current from the source by the electrochemical process
  • Practical considerations
  • Atmospheric Pressure Chemical Ionization
  • Atmospheric Pressure Photoionization (APPI)
  • Atmospheric Pressure Secondary Ion Mass Spectrometry (APSIMS)
  • Desorption electrospray ionization (DESI)
  • Direct analysis in real time (DART)
  • Inorganic Ionization Sources
  • Thermal ionization source
  • Spark source
  • Glow discharge source
  • Inductively coupled plasma source
  • Practical considerations
  • Gas-Phase Ion-Molecule Reactions
  • Formation and Fragmentation of Ions: Basic Rules
  • Electron ionization and photoionization under vacuum
  • Ionization at low pressure or at atmospheric pressure
  • Proton transfer
  • Adduct formation
  • Formation of aggregates or clusters
  • Reactions at the interface between source and analyzer


Details
 
AUTHOR(S)/ED(S) Edmond de Hoffmann, Vincent Stroobant
BINDING Paperback
PUBLISHED September 2007
NO. PAGES 502
AVAILABILITY In stock for immediate despatch

Price:
£34.95

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