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NMR Primer: An HSQC-Based
Approach
(with vector animations)
by
Steven M. Pascal
Massey University, New Zealand
with animations by Jennie M. McKelvie
This new textbook provides a basic understanding of some simple
and not-so-simple NMR concepts, primarily as they pertain to the key two-dimensional
protein NMR experiment, the 1H,15N-HSQC, along with
its variants and extensions.
One of the unique aspects of the book is the availability of animations
of most pulse sequences, which greatly increase the ease with which the
student can understand
Sample Animation
Click on the play button below ()
to start the animation (choose slow motion for ...slower play)
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Key points
The HSQC explained from first physical principles using vector diagrams
Building on the HSQC, double and triple resonance experiments for
chemical shift assignment, NOE and relaxation studies are described
User-navigable colour-coded vector animations for most pulse sequences:
see how the magnetisation actually evolves
Extended appendices cover sensitivity-enhancement, TROSY, HMQC, extraction
of dynamic information from relaxation data, artefact suppression, quadrature
schemes in the direct and indirect dimensions and more
Accessible to the beginner but also helpful to the specialist: includes
advanced concepts but primarily from a physical (non-formal) point of
view