NMR Primer: An HSQC-Based Approach
(with vector animations)

by

Steven M. Pascal

Massey University, New Zealand

with animations by Jennie M. McKelvie

This new textbook provides a basic understanding of some simple and not-so-simple NMR concepts, primarily as they pertain to the key two-dimensional protein NMR experiment, the ¹H,¹⁵N-HSQC, along with its variants and extensions.

One of the unique aspects of the book is the availability of animations of most pulse sequences, which greatly increase the ease with which the student can understand

Sample Animation

Click on the play button below () to start the animation (choose slow motion for ...slower play)

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Key points

• The HSQC explained from first physical principles using vector diagrams
• Building on the HSQC, double and triple resonance experiments for chemical shift assignment, NOE and relaxation studies are described
• User-navigable colour-coded vector animations for most pulse sequences: see how the magnetisation actually evolves
• Extended appendices cover sensitivity-enhancement, TROSY, HMQC, extraction of dynamic information from relaxation data, artefact suppression, quadrature schemes in the direct and indirect dimensions and more
• Accessible to the beginner but also helpful to the specialist: includes advanced concepts but primarily from a physical (non-formal) point of view