| Author | Message | ||
     Bernard North (bnorth) Junior Member Username: bnorth Post Number: 7 Registered: 5-2007 |
fantastic. many thanks, Dr Trygg,for such a prompt and helpful response | ||
| Johan Trygg (trygg) Junior Member Username: trygg Post Number: 6 Registered: 1-2006 |
Dear Bernard, Yes, you can do that also when you have two different samples taken from the same individual but from different locations. Good luck with you analysis, regards, Johan Trygg Computational Life Science Cluster (CLiC) Ume� University, Sweden | ||
| Bernard North (bnorth) Junior Member Username: bnorth Post Number: 6 Registered: 5-2007 |
I wonder if I can ask a question please ? Is OPLS-DA appropriate for paired data ? For example if I took diseased and healthy tissue from each of a series of patients and wished to compare diseased v healthy can I use OPLS-DA in the same way I would if I had, say , unpaired data of diseased tissue from patients compared to healthy tissue from controls. I thought OPLS-DA might be OK if the orthogonal signal correction in some way factored out the patient effects many thanks in advance |