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Dr.K.Balasubramanian (drkbala)
Advanced Member
Username: drkbala

Post Number: 22
Registered: 9-2006
Posted on Wednesday, March 25, 2009 - 5:58 pm:   

Not Yet.It is underway.We are workin on it.
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Art Springsteen (artspring)
Junior Member
Username: artspring

Post Number: 10
Registered: 2-2003
Posted on Monday, February 09, 2009 - 9:58 am:   

Hi Jerry,

There are no commercially available, FDA approved NIR blood glucose analyzers that I am familiar with. Speaking with Jerry Workman, who is sort of the guru in the field, he mentions (and this was over a year ago) that there are over 170 patents on in-vivo blood blood glucose analysis and none of them work. (and I think I've worked with about half the people working on this. And if you think about it, it really is like looking for a needle ina (large) haystack- there are so many competing 'glucose-like' structures in biological systems.
But people keep trying because the Holy Grail is worth a lot of money...
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Howard Mark (hlmark)
Senior Member
Username: hlmark

Post Number: 221
Registered: 9-2001
Posted on Monday, February 09, 2009 - 8:36 am:   

The discussion turned out to be very timely. I just received a message containing a link to this URL, which is titled "Measurement of tissue saturation levels using portable near-IR spectroscopy in clinically healthy dogs:

http://www.spectroscopynow.com/coi/cda/detail.cda?id=20098&type=Feature&chId=2&page=1

I haven't read it myself, yet, but it looks like it should have some pertinent info.

\o/
/_\
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iyas (iyas)
Advanced Member
Username: iyas

Post Number: 21
Registered: 7-2007
Posted on Monday, February 09, 2009 - 2:20 am:   

dear all
there are many devices measure the o2 in blood
and they are important in the field of emergency, but they lack the ability to measure the o2 if the blood stopped like in accidents or in heart attack,
but there was anew method to measure the o2 in the tissue and this is very useful

and they use NIR IN THE Measurement
BUT I DO NOT KNOW WHICH MECHANISM
It may be the dispersive mechanism
i remembered a name one of these device may be INSPECTRA ST02

for the glucose devices measurement
no commercial devices in the market until now
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Howard Mark (hlmark)
Senior Member
Username: hlmark

Post Number: 219
Registered: 9-2001
Posted on Sunday, February 08, 2009 - 4:50 pm:   

Jerry - the problem of glucose measurement by NIR is of great interest, for both scientific and commercial reasons. At one point I heard an estimate that at least 60 groups were working on it worldwide. As of yet I don't know of anyone's having solved it to the satisfaction of the regulatory authorities such as the FDA.

The problem of oxygenation is much simpler, and there is a device on the market called the "Pulse Oximeter". I don't recall who the manufacturer is, but a patent search should turn it up in short order.

\o/
/_\
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Jerry Jin (jcg2000)
Junior Member
Username: jcg2000

Post Number: 6
Registered: 1-2009
Posted on Sunday, February 08, 2009 - 3:32 pm:   

Is anybody aware of a commercialized in vivo NIR glucose monitor approved by FDA?

Obviously Gary Small and Mark Arnold in the University of Iowa have done a lot of great work on NIR measurement of blood glucose. Who are the gurus in NIR measurement of blood hemoglobin?

Is there a commercialized NIR hemoglobin/deoxyhemoglobin monitor?

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