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AMaizes
Posted on Tuesday, February 13, 2001 - 1:23 pm:   

I'm interested in contacting companies able to design frequency domain near infrared spectroscopy units for oxygen analysis. Do you have any suggestions?
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hlmark
Posted on Tuesday, February 13, 2001 - 1:54 pm:   

Try contacting the FTIR companies: Bomem, Bruker, Digilab, Nicolet, Perkin-Elmer, to name a few. While traditionally mid-IR companies, they all include NIR capability now. As Bruce reminded us recently, there is a list of them on this website.

Also, "oxygen analysis" is rather vague. You will need to be more specific when you talk to them.

Howard
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AMaizes
Posted on Wednesday, February 14, 2001 - 7:40 pm:   

I should be more specific. I'm interested in a medical application of frequency domain near infra-red spectroscopy for oxygen-hemoglobin/deoxyhemoglobin saturation percent analysis.
I know the application, I'm interested in the hardware. Thanks.
Allen Maizes, M.D.
New York, New York
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Andrew McGlone (Mcglone)
Posted on Wednesday, February 14, 2001 - 8:36 pm:   

I know ISS inc. sell an IMOS system for your purpose
(http://www.iss.com/products/oxiplex/oxiplex.htm) with two detector channels. I've not checked it out at all as it was too expensive (~US$40K??) for my budget. (NB. various names seemed to be used for this technology: IMOS = intensity modulated optical spectrometry; FDPM = frequency domain photon migration; PDS = phase modulation system. I prefer IMOS because of the vowels!!)

From my limited observation I sense that most groups still build there own systems. I'm currently considering building my own, for a different purpose to yours, following the general approach of the group at UC Irvine (Pham et al.,2000, Review of Scientific Instruments, pg 2500-2513.). Basically it's buy an RF Network Analyser (makes the relevant amplitude/phase measurement easy ... or so they say!!), some laser diodes and a photomultipler (or APD if you have enough light).

A good technical reference for IMOS instrumentation is: Chance, Cope, Gratton,Ramanujam,Tromberg (1998) Review of Scientific Instruments 69, 3457.

I'm still evaluating my own options here so any input from knowledgeable others would be appreciated too.
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Emilio
Posted on Thursday, June 27, 2002 - 4:03 am:   

I am looking into an application similar to the one described by AMaizes. In my case I want to scan at a variable depth in biological tissue and bone. Which manufacturer would you suggest?

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