| Author | Message | ||
     Simin44 |
I just started to work on a new project. The subject is to detect polymer (for tablet coating) molecule diffusion during drying and curing process using NIRS. I have already taken courses in cheometrics and working with NIR machine and vision software. Currently I am casting the polymer mix (polyacrylate 10% solid content in water). Beside one challenge that I am trying to solve it (keeping polymer cast thickness constant), I have two questions, first, has anybody have done this type of work or has references about it (I looked but I could not find it), second question is about the feasibility of this study. Is NIR able to detect crosslinking in polymer molecules? How can I detect the diffusion since drying process causes cross-linking of polymer molecules the way that no C-H or N-H or OH bound is formed directly, however does any cross-linking affect neighboring C-H or � stretches the way that can be detected with NIRS? If not, which tech is better to use? Thanks a lot for your input. (Also detection of water content as a sign of drying progress is not my objective) | ||
| hlmark |
Simin - the Handbook of NIR Analysis (2nd ed, Marcel Dekker, 2001) contains a chapter on analysis of polymers, which includes a graph of the behavior of spectra as a reaction proceeds. It also includes discussion of NIR of many classes of polymers, as well as several spectra showing the spectral changes found during reaction. It may not answer your exact question, but I think you'll find much useful info there. Howard \o/ /_\ |