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Erik Skibsted
Posted on Wednesday, May 21, 2003 - 3:02 am:   

Hi

First thanks for a great conference in Cordoba, it was a great pleasure to attend. With many interesting and inspiring posters and presentations (not forgetting the suprb food)

I had a question from a collegue which I will post here. He is interrested in measuring insulin and water in intact vials as the leave the filling station, so thats with the speed of several vials/sec.

I suggested to contact Brimrose or Zeiss with their fast instruments, or meaby a single wavelength fluorescence detector? The vials are app. 8mm (and app. 8 cm long) thick made of glass that does not absord in the NIR spectra and the sample looks a little like milk, white slurry because of the insulin crystals. So we have multible problems

1) we need a very fast measurement
2) highly scattering sample
3) high water concentration
4) there is a risk of settlement of the crystals
5) varying particle size

If anyone have some pointers for me or could help me out with some references, both about high-speed measurements and NIR/quantitative insulin models

then my day will be a lot better ;-)

Kindly regards
Erik Skibsted
Novo Nordisk and University of Amsterdam
www.tipb.nl
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Gabi Levin
Posted on Wednesday, May 21, 2003 - 7:30 am:   

Dear Erik,
I can only suggest that you contact me at Brimrose for further discussion and information.

[email protected].

Many thanks.

Gabi Levin

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