Abstract
European Journal of Mass Spectrometry
Volume 13 Issue 1, Pages 35–39 (2007)
doi: 10.1255/ejms.845
Proteomic strategies for rapid characterization of micro- organisms
C. Fenselau, S. Russell, S. Swatkoski and N. Edwards*
University of Maryland, Deptartment of Chemistry & Biochemistry, and
Center for Bioinformatics and Computational Biology, College Park, MD 20742, USA
Bioinformatic considerations are offered to illustrate strengths and limitations of the characterization of Bacillus spores based on proteomic interpretation of matrix-assisted laser desorption/ionization spectra. In particular, species-specific biomarkers are evaluated in the context of both experimental access and uniqueness in silico.
Keywords: bioinformatics, proteomics, biomarkers, proteins, MALDI, spores, anthrax, Bacillus, species specificity
Full-text article (306 kB) (Open Access Paper)
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